Fig 2. Reported mortality associated with 2009 Influenza A (H1N1) associated critical illness.

We describe the mortality based on temporal (early, late and prolonged enrollment), study (study size, single center compared to multicenter and adults compared to pediatrics), and the geographic location and socioeconomic development from the included studies. The black squares represent the point estimate and 95% confidence intervals (CIs) around the mortality for each subgroup. The black diamond is the summary or overall combined estimate of mortality associated with the 2009 Influenza A (H1N1) pandemic.