Table 1. Incidental histology findings in REAR mice.
| Age | Sex/mice# | Lung | Mammay gland | Prostate |
|---|---|---|---|---|
| 9-17wks | Females (15) | NSF | Minimal to mild hyperplasia (7) | NA |
| Males (0) | NSF | NA | NSF | |
| 26-38wks | Females (16) | NSF | Minimal hyperplasia (5) | NA |
| Males (2) | NSF | NA | Marked medial vascular hypertrophy (1) | |
| 1–2 years | Females (13) | Alveolar hyperplasia (1) | Minimal hyperplasia (2) | NA |
| Pulmonary adenoma (3) | Mammary adenocarcinoma (1) | |||
| Pulmonary carcinoma (1) | ||||
| Mammary carcinoma metastasis (1) | ||||
| Males (7) | Pulmonary adenoma (2) | NA | Marked medial vascular hypertrophy (1) | |
| Pulmonary carcinoma (2) | NA | Leiomyosarcoma vascular (1) |
NSF—no significant finding
NA—not applicable
Number of mice are in brackets