Table 2. Selected list of gene transcripts correlated with age and BMI*.
| Symbol | Gene name | P value | R | Symbol | Gene name | P value | R | |
|---|---|---|---|---|---|---|---|---|
| Gene transcripts positively correlated with age | Gene transcripts negatively correlated with age | |||||||
| TSC2 | tuberous sclerosis 2 | 0.004 | 0.81 | PFKFB2 | 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 2 | 0.001 | 0.87 | |
| SNAI2 | snail family zinc finger 2 | 0.004 | 0.81 | PSMD5 AS1 | proteasome (prosome, macropain) 26S subunit, non- ATPase, 5 –antisense RNA 1 | 0.001 | 0.87 | |
| SLC35E1 | solute carrier family 35, member E1 | 0.003 | 0.81 | CD14 | CD14 molecule | 0.001 | 0.84 | |
| DCUN1D2 AS2 | DCN1, Defective In Cullin Neddylation 1 –antisense RNA 2 | 0.004 | 0.80 | FCGR2B | Fc fragment of IgG, low affinity IIb, receptor | 0.002 | 0.82 | |
| PREX2 | phosphatidylinositol 3,4,5 trisphosphate dependent Rac exchange factor 2 | 0.005 | 0.80 | TAGAP | T cell activation RhoGTPase activating protein | 0.003 | 0.82 | |
| IFITM2 | interferon induced transmembrane protein 2 | 0.004 | 0.79 | OR2M3 | olfactory receptor, family 2, subfamily M, member 3 | 0.002 | 0.82 | |
| DOT1L | DOT1 like histone H3K79 methyltransferase | 0.004 | 0.79 | SLC8A1 AS1 | solute carrier 8 family A1 –antisense RNA 1 | 0.003 | 0.82 | |
| STXBP4 | syntaxin binding protein 4 | 0.002 | 0.79 | DIRC3 | disrupted in renal carcinoma 3 | 0.003 | 0.81 | |
| MOV10 | Moloney leukemia virus 10, homolog | 0.005 | 0.79 | ATP8B4 | ATPase, class I, type 8B, member 4 | 0.003 | 0.81 | |
| CNNM3 | cyclin M3 | 0.006 | 0.78 | RASSF2 | Ras association (RalGDS/AF 6) domain family member 2 | 0.004 | 0.80 | |
| CDK2 | cyclin dependent kinase 2 | 0.005 | 0.78 | MMP24 AS1 | matrix metallopeptidase 24 –antisense RNA 1 | 0.000 | 0.80 | |
| RAD51 AS1 | RAD51 antisense RNA 1 | 0.007 | 0.78 | FGD2 | FYVE, RhoGEF and PH domain containing 2 | 0.005 | 0.79 | |
| ZNF546 | zinc finger protein 546 | 0.005 | 0.77 | HNF1A AS1 | Hepatocyte nuclear factor 1 alpha—antisense RNA 1 | 0.006 | 0.78 | |
| TRIB2 | tribbles pseudokinase 2 | 0.005 | 0.77 | TCEAL3 | transcription elongation factor A (SII) like 3 | 0.007 | ||
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.007 | 0.77 | CYTIP | cytohesin 1 interacting protein | 0.007 | 0.77 | |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 | 0.005 | 0.77 | NCF1B | neutrophil cytosolic factor 1B | 0.007 | 0.77 | |
| XAB2 | XPA binding protein 2 | 0.007 | 0.76 | SLC5A8 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 | 0.007 | 0.77 | |
| TAF6L | TAF6 like RNA polymerase II, p300/CBP associated factor (PCAF) associated factor | 0.008 | 0.76 | RAB11FIP1 | RAB11 family interacting protein 1 | 0.007 | 0.77 | |
| GMCL1 | germ cell less, spermatogenesis associated 1 | 0.006 | 0.75 | POTEE | POTE ankyrin domain family, member E | 0.007 | 0.76 | |
| RING1 | ring finger protein 1 | 0.009 | 0.75 | PPEF1 AS1 | protein phosphatase, EF hand calcium binding domain 1 antisense RNA 1 | 0.011 | 0.76 | |
| Gene transcripts positively correlated with BMI | Gene transcripts negatively correlated with BMI | |||||||
| CYP7A1 | cytochrome P450, family 7, subfamily A, polypeptide 1 | 0.001 | 0.85 | ERCC2 | excision repair cross complementation group 2 | 0.002 | 0.80 | |
| TMEM235 | transmembrane protein 235 | 0.001 | 0.82 | TRIM49 | tripartite motif containing 49 | 0.004 | 0.80 | |
| CCDC79 | coiled coil domain containing 79 | 0.005 | 0.79 | GDF11 | growth differentiation factor 11 | 0.005 | 0.79 | |
| SLC26A5 | solute carrier family 26 (anion exchanger), member 5 | 0.005 | 0.78 | ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.006 | 0.78 | |
| ZNF852 | zinc finger protein 852 | 0.006 | 0.78 | AANAT | aralkylamine N acetyltransferase | 0.006 | 0.78 | |
| DDR1 | discoidin domain receptor tyrosine kinase 1 | 0.004 | 0.77 | LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | 0.004 | 0.78 | |
| LRRC2 | leucine rich repeat containing 2 | 0.007 | 0.77 | BAAT | bile acid CoA: amino acid N acyltransferase | 0.007 | 0.78 | |
| LYPD6 | LY6/PLAUR domain containing 6 | 0.008 | 0.77 | DIEXF | digestive organ expansion factor homolog | 0.003 | 0.77 | |
| FFAR1 | free fatty acid receptor 1 | 0.008 | 0.76 | FGD1 | FYVE, RhoGEF and PH domain containing 1 | 0.008 | 0.77 | |
| IGLV4 69 | immunoglobulin lambda variable 4 69 | 0.008 | 0.76 | SLC35B1 | solute carrier family 35, member B1 | 0.010 | 0.76 | |
| CDHR3 | cadherin-related family member 3 | 0.010 | 0.76 | TMEM243 | transmembrane protein 243 | 0.002 | 0.76 | |
| RGS21 | regulator of G protein signaling 21 | 0.011 | 0.75 | HEXIM1 | hexamethylene bis acetamide inducible 1 | 0.010 | 0.76 | |
| ATXN3L | ataxin 3 like | 0.008 | 0.75 | MICB | MHC class I polypeptide-related sequence B | 0.010 | 0.75 | |
| RASSF10 | Ras association (RalGDS/AF 6) domain family (N terminal) member 10 | 0.012 | 0.75 | HIST1H2AJ | histone cluster 1, H2aj | 0.010 | 0.75 | |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.013 | 0.74 | CCDC28B | coiled coil domain containing 28B | 0.015 | 0.73 | |
| HAO2 | hydroxyacid oxidase 2 | 0.007 | 0.74 | ZNF846 | zinc finger protein 846 | 0.008 | 0.73 | |
| RIC8A | RIC8 guanine nucleotide exchange factor A | 0.014 | 0.73 | PGP | phosphoglycolate phosphatase | 0.003 | 0.73 | |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.008 | 0.73 | RHOA IT1 | RHOA intronic transcript 1 | 0.004 | 0.73 | |
| AADACL4 | arylacetamide deacetylase like 4 | 0.011 | 0.73 | FAM174B | family with sequence similarity 174 | 0.016 | 0.72 | |
| ANK1 | ankyrin 1 | 0.008 | 0.73 | NXPH4 | neurexophilin 4 | 0.014 | 0.72 | |
*Top 20 gene transcripts highly correlated with age and BMI are shown.
BMI = body mass index, r = correlation coefficient