Fig 3. Influence of HIV infection on dendritic cell migration and activation in ectocervical explants.

DC migration and activation was compared between HIV-infected (n = 6) and uninfected participants (n = 8). Ectocervical explants from HIV-infected and uninfected participants were stimulated for 24 hours with Medium, cytokines or TLR agonists. Migration and activation of DCs was evaluated and compared between the two groups of participants for the three DC subsets and stimulation conditions. Data presented as Box and Whisker plots of fold migration above background (medium alone). Mann-Whitney test was used for statistical analyses. * P-values <0.05