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. 2016 May 15;27(10):1561–1569. doi: 10.1091/mbc.E16-01-0018

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© 2016 Jaqaman et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 3: — Multiscale live-cell imaging and analysis framework to connect molecular density and mobility to local cell protrusion. (a) Multiscale microscopy intercalates high-speed, single-molecule, superresolution imaging with slower, diffraction-level imaging of the cell. (b) Data are extracted to construct single-molecule trajectories and track the cell edge or segment adhesions. (c) Molecular properties are connected to cell protrusive activity.