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. 2016 May 15;27(10):1694–1705. doi: 10.1091/mbc.E15-12-0816

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© 2016 Brion et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 2: — Definition of ESR genes in L. kluyveri using S. cerevisiae ESR. (A) Comparison of the sets of ESR genes in L. kluyveri (horizontal rectangle) and S. cerevisiae (vertical rectangle). The areas are proportional to the corresponding number of genes (indicated inside the boxes). The GO term enrichment is indicated in the boxes. CR, coregulated; DR, down-regulated; UR, up-regulated. The New box corresponds to the L. kluyveri ESR genes whose orthologues are not among S. cerevisiae ESR genes. (B) Schematic of the principle of the method used to define L. kluyveri ESR genes based on S. cerevisiae ESR genes. (C) Clustering of all L. kluyveri ESR gene expressions after normalization with the reference medium YPD (yellow, up-regulated; blue, down-regulated).