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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Eur J Clin Pharmacol. 2016 Feb 26;72(6):681–687. doi: 10.1007/s00228-016-2029-x

Table 1.

Baseline demographics of the 486 INVEST-GENES participants

Characteristics This study (n=486) INVEST (n=22,576) p
Age, mean (SD), years 66 (10) 66 (10) 0.42
Women 285 (59%) 11770 (52%) 0.23
Baseline BP, mean (SD), mmHg
  Systolic 151 (18) 148 (18) 0.0001
  Diastolic 87 (10) 87 (12) 0.0015
Race/ethnicity 0.0006
  White 214 (44%) 10925 (48%)
  Black 77 (16%) 3029 (13%)
  Hispanic 189 (39%) 8045 (36%)
  Other/multiracial 6 (1%) 577 (3%)
BMI, mean (SD), kg/m2 30 (6) 29 (7) 0.04
Smoking history 189 (39%) 2265 (41%) 0.31
Past Medical History
Myocardial infarction 117 (24%) 7218 (32%) 0.65
Angina pectoris 348 (72%) 15045 (67%) 0.19
Stroke/TIA 38 (8%) 1629 (7%) 0.46
Left ventricular hypertrophy 88 (18%) 4948 (22%) 0.06
Heart failure (class I-III) 15 (3%) 1256 (6%) 0.73
Peripheral vascular disease 53 (11%) 2699 (12%) 0.91
Diabetes 137 (28%) 6401 (28%) 0.997
Hypercholesterolemia 254 (52%) 12448 (55%) 0.34
Renal impairment 8 (2%) 424 (2%) 0.9