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. Author manuscript; available in PMC: 2017 May 12.
Published in final edited form as: J Phys Chem B. 2016 May 3;120(18):4195–4203. doi: 10.1021/acs.jpcb.6b00927

Table 3.

Rate and Activation Enthalpy for Stem-Loop Hairpin to Duplex Conversion at 37 °C.1

n k37°C2 (M−1 s−1) / × 103 ΔH‡ 3 (kcal mol −1)
6 15.2 ± 2.0 29.1 ± 3.2
7 44.4 ± 2.7 6.76 ± 0.57
8 6.2 ± 0.6 -
9 40.2 ± 1.6 -
10 5.7 ± 0.4 35.8 ± 4.1
11 31.4 ± 2.3 21.4 ± 3.6
12 5.1 ± 0.9 -
13 26.8 ± 1.7 -
14 6.3 ± 0.8 41.0 ± 5.1
25 11.0 ± 0.5 -
30 4.6 ± 0.2 -
1

In 20 mM sodium phosphate, 100 mM NaCl, pH 7.0.

2

Errors represent standard deviation from a minimum of three experiments.

3

Errors represent the uncertainty derived from fitting the rate constants at four different temperatures to the Eyring equation.