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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Pediatr Infect Dis J. 2016 Jun;35(6):649–654. doi: 10.1097/INF.0000000000001131

Table 3.

Significant adjusted associations of retrospective memory outcomes with HIV disease severity in participants with PHIV.

Outcome Disease severity measure Covariate/

Level		 Adjusted Results*
Mean (95%
Confidence
Interval)/

Estimat
(Standard Error)		 P-
Value
Immediate Design
Memory1 		Age at peak HIV RNA viral load 0–3.0 years 9.06 (8.54, 9.58) 0.04
3.1 years or
older		 8.17 (7.49, 8.85)
Design Recognition2 Log10 HIV RNA viral load at study
entry		 (continuous) −0.38 (0.19) 0.05
Age at peak HIV RNA viral load (continuous) −0.11 (0.05) 0.03
Age at peak HIV RNA viral load 0–3.0 years 9.07 (8.52, 9.62) 0.003
3.1 years or
older		 7.73 (7.04, 8.43)
Verbal Learning3 CD4% at study entry (continuous) 0.04 (0.02) 0.03
CD4% ≥ 25 at study entry < 25% 7.04 (6.33, 7.76) 0.01
≥ 25% 8.04 (7.55, 8.54)
Verbal Delayed Recall4 Age at peak HIV RNA viral load ≤ 3 years 9.07 (8.50,9.65) 0.02
3.1–5 years 9.88 (8.67,11.09)
> 5 years 8.03 (7.20,8.87)
*

The adjusted mean and 95% CI are provided for each level of categorical covariates, and for continuous covariates the adjusted mean increase (and standard error) in outcome for each 1 unit change in predictor is presented.

1

Design memory is adjusted for caregiver is biological relation

2

Design recognition is not adjusted because no covariates met model-building criteria

3

Verbal learning is adjusted for age at study entry, biological relation to caregiver, and caregiver is high school graduate

4

Verbal Delayed recall is adjusted for age at study entry, black race, caregiver is biological relation and caregiver is high school graduate