Table 3.
Incidence rates of cancer per 100,000 person-years in HIV-positive children in South Africa.
| Person-years at risk | No. of cancer cases | Incidence rate (95% CI) | |
|---|---|---|---|
| Any cancer | 29,348 | 24 | 82 (55 – 122) |
| AIDS defining cancer | |||
| Any | 29,360 | 19 | 65 (41 – 102) |
| KS | 29,373 | 10 | 34 (18 – 63) |
| NHL | 29,393 | 9 | 31 (16 – 59) |
| Non AIDS defining cancer | 29,393 | 5 | 17 (7 – 41) |
| Gender | |||
| Male | 14,919 | 14 | 94 (56 – 158) |
| Female | 14,425 | 10 | 70 (37 – 129) |
| Age at enrolment | |||
| ≤ 1 year | 6,343 | 2 | 32 (8 – 126) |
| 1 to <3 years | 7,362 | 5 | 68 (28 – 163) |
| 3 to <5 years | 4,908 | 5 | 102 (42 – 245) |
| 5 to <10 years | 8,197 | 7 | 85 (41 – 179) |
| ≥ 10 years | 2,534 | 5 | 197 (82 – 474) |
| Immunodeficiency at enrolment | |||
| No / mild | 6,282 | 2 | 32 (8 –127) |
| Advanced / severe | 12,395 | 9 | 73 (38 – 140) |
| Missing | 10,666 | 13 | 122 (71 -210) |
| ART treatment (time updated) | |||
| Not on ART | 5,464 | 12 | 220 (125 – 387) |
| On ART | 23,864 | 12 | 50 (29 – 89) |
| Missing, unclear | 16 | 0 | - |
| Calendar year of starting ART | |||
| Before 2005 | 5,197 | 9 | 173 (90 – 333) |
| ≥ 2005 to 2009 | 20,627 | 12 | 58 (33 – 102) |
| ≥ 2010 | 1,822 | 1 | 55 (8 – 390) |
| Missing / never starting | 1,697 | 2 | 118 (30 – 471) |
| Calendar year of enrolment | |||
| < 2005 | 9,012 | 10 | 111 (60 – 206) |
| ≥ 2005 | 20,331 | 14 | 69 (41 – 116) |
ART, antiretroviral therapy; KS, Kaposi Sarcoma; CI, confidence interval.