Table 4. Association between the prevalence, treatment and control of hypertension and the prevalence of MCI by age.
| Prevalence of MCI | N (%) | Unadjusted OR (95% CI), P | Adjusteda OR (95% CI), P |
|---|---|---|---|
| 60–69 years | |||
| Normotensives (reference group) | 32/324 (9.9) | ||
| Hypertensives | 52/424 (12.3) | 1.28 (0.80–2.03), 0.306 | 1.90 (1.10–3.29), 0.022 |
| Untreated hypertensives (reference group) | 23/142 (16.2) | ||
| Treated hypertensives | 29/282 (10.3) | 0.59 (0.33–1.07), 0.082 | 0.41 (0.23–0.71), 0.002 |
| Uncontrolled hypertensives among hypertensives (reference group) | 38/280 (13.6) | ||
| Controlled hypertensives among hypertensives | 14/144 (9.7) | 0.69 (0.36–1.31), 0.255 | 0.53 (0.29–0.97), 0.039 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 15/138 (10.9) | ||
| Controlled hypertensives among treated hypertensives | 14/144 (9.7) | 0.88 (0.41–1.91), 0.751 | 0.72 (0.34–1.51), 0.388 |
| 70–79 years | |||
| Normotensives (reference group) | 40/278 (14.4) | ||
| Hypertensives | 135/821 (16.4) | 1.17 (0.80–1.72), 0.419 | 1.22 (0.77–1.94), 0.390 |
| Untreated hypertensives (reference group) | 47/263 (17.9) | ||
| Treated hypertensives | 88/558 (15.8) | 0.86 (0.58–1.27), 0.449 | 0.80 (0.54–1.19), 0.277 |
| Uncontrolled hypertensives among hypertensives (reference group) | 103/594 (17.3) | ||
| Controlled hypertensives among hypertensives | 32/227 (14.1) | 0.78 (0.51–1.20), 0.263 | 0.77 (0.51–1.15), 0.201 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 56/331 (16.9) | ||
| Controlled hypertensives among treated hypertensives | 32/227 (14.1) | 0.81 (0.50–1.29), 0.370 | 0.78 (0.50–1.22), 0.278 |
| ⩾80 years | |||
| Normotensives (reference group) | 14/55 (25.5) | ||
| Hypertensives | 46/163 (28.2) | 1.15 (0.57–2.31), 0.691 | 2.44 (0.60–9.94), 0.213 |
| Untreated hypertensives (reference group) | 22/58 (37.9) | ||
| Treated hypertensives | 24/105 (22.9) | 0.49 (0.24–0.98), 0.042 | 0.56 (0.15–2.11), 0.391 |
| Uncontrolled hypertensives among hypertensives (reference group) | 36/117 (30.8) | ||
| Controlled hypertensives among hypertensives | 10/46 (21.7) | 0.63 (0.28–1.40), 0.251 | 0.50 (0.17–1.52), 0.225 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 14/59 (23.7) | ||
| Controlled hypertensives among treated hypertensives | 10/46 (21.7) | 0.89 (0.36–2.25), 0.810 | 0.47 (0.13–1.75), 0.259 |
Abbreviations: CI, confidence interval; MCI, mild cognitive impairment; OR, odds ratio.
a
Adjusted for age, education level, marital status, physical activity, smoking and drinking status, body mass index, triglycerides, high-density lipoprotein, low-density lipoprotein, diabetes mellitus (yes/no), history of stroke and family history of dementia.