Association between the prevalence, treatment and control of hypertension and the prevalence of MCI in participants aged at least 65 years by gender (n=1707).
| Prevalence of MCI | N (%) | Unadjusted OR (95% CI), P | Adjusteda OR (95% CI), P |
| Male | |||
| Normotensives (reference group) | 32/238 (13.4) | ||
| Hypertensives | 91/479 (19.0) | 1.51 (0.98–2.34), 0.065 | 2.05 (1.07–3.90), 0.030 |
| Untreated hypertensives (reference group) | 39/164 (23.8) | ||
| Treated hypertensives | 52/315 (16.5) | 0.63 (0.40–1.01), 0.055 | 0.48 (0.26–0.87), 0.016 |
| Uncontrolled hypertensives among hypertensives (reference group) | 71/331 (21.5) | ||
| Controlled hypertensives among hypertensives | 20/148 (13.5) | 0.57 (0.33–0.98), 0.043 | 0.44 (0.22–0.85), 0.014 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 32/167 (19.2) | ||
| Controlled hypertensives among treated hypertensives | 20/148 (13.5) | 0.66 (0.36–1.21), 0.180 | 0.56 (0.26–1.19), 0.130 |
| Female | |||
| Normotensives (reference group) | 37/257 (14.4) | ||
| Hypertensives | 117/733 (16.0) | 1.13 (0.76–1.69), 0.552 | 1.49 (0.81–2.73), 0.196 |
| Untreated hypertensives (reference group) | 44/229 (19.2) | ||
| Treated hypertensives | 73/504 (14.5) | 0.71 (0.47–1.08), 0.106 | 0.61 (0.36–1.01), 0.053 |
| Uncontrolled hypertensives among hypertensives (reference group) | 90/536 (16.8) | ||
| Controlled hypertensives among hypertensives | 27/179 (13.7) | 0.79 (0.49–1.25), 0.313 | 0.61 (0.35–1.07), 0.085 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 46/307 (15.0) | ||
| Controlled hypertensives among treated hypertensives | 27/179 (13.7) | 0.90 (0.54–1.51), 0.691 | 0.69 (0.37–1.27), 0.230 |
| All | |||
| Normotensives (reference group) | 69/495 (13.9) | ||
| Hypertensives | 208/1212 (17.2) | 1.28 (0.95–1.72), 0.102 | 1.69 (1.09–2.61), 0.018 |
| Untreated hypertensives (reference group) | 83/393 (21.1) | ||
| Treated hypertensives | 125/819 (15.3) | 0.67 (0.49–0.92), 0.012 | 0.56 (0.39–0.83), 0.003 |
| Uncontrolled hypertensives among hypertensives (reference group) | 161/867 (18.6) | ||
| Controlled hypertensives among hypertensives | 47/345 (13.6) | 0.69 (0.49–0.98), 0.040 | 0.55 (0.36–0.84), 0.005 |
| Uncontrolled hypertensives among treated hypertensives (reference group) | 78/474 (16.5) | ||
| Controlled hypertensives among treated hypertensives | 47/345 (13.6) | 0.80 (0.54–1.19), 0.266 | 0.66 (0.42–1.05), 0.082 |
Abbreviations: CI, confidence interval; MCI, mild cognitive impairment; OR, odds ratio.
a
Adjusted for age, education level, marital status, physical activity, smoking and drinking status, body mass index, triglycerides, high-density lipoprotein, low-density lipoprotein, diabetes mellitus (yes/no), history of stroke and family history of dementia.