Table 1. Cox regression analysis of risk factors for cancer-related death in lung cancer patients.

Characteristics	Univariate analysis		Multivariate analysis
	HR (95% CI)	P-valuea	HR (95% CI)	P-valuea
ZNF322A protein expression
Normal expression	1.00		1.00
Overexpression	2.75 (1.17–6.46)	0.020	3.26 (1.25–8.49)	0.016
Age
<65 year-old	1.00		—b
⩾65 year-old	0.81 (0.48–1.38)	0.433	—b	—b
Gender
Female	1.00		—b
Male	1.48 (0.85–2.57)	0.165	—b	—b
Smoking habit
Non-smoker	1.00		1.00
Smoker	1.87 (1.02–3.42)	0.044	1.93 (1.01–3.68)	0.046
Type
SCC	1.00		—b
ADC	0.96 (0.53–1.75)	0.897	—b	—b
Stage
Stage I–II	1.00		1.00
Stage III–IV	2.17 (1.25–3.77)	0.006	1.54 (0.80–2.96)	0.194
T stage
Stage 1–2	1.00		1.00
Stage 3–4	2.21 (1.03–4.74)	0.042	1.44 (0.45–4.57)	0.539
N stage
N0	1.00		—b
⩾N1	1.46 (0.84–2.52)	0.180	—b	—b
M stage
M0	1.00		—b
⩾M1	1.94 (0.69–5.44)	0.209	—b	—b

Abbreviations: ADC, adenocarcinoma; CI, confidence interval; HR, hazard ratio; SCC, squamous cell carcinoma.

^aBold values indicate statistical significance (P<0.05).

^bThe variables without significant HR in the univariate analysis were not included in the multivariate analysis.