Table 1.
Structure and clinical applications of different anti-selectin agents described in this review.
Type | Name | N° | Structure | Tumor type tested | Reference |
---|---|---|---|---|---|
Heparin derivatives | Heparin sulfate | 1 | ![]() |
Human sarcoma, melanoma, and colon carcinoma | (88) |
Dermatan sulfate | 2 | ![]() |
Colon carcinoma and melanoma | (89) | |
6-O-sulfated chitosan | 3 | ![]() |
Human melanoma | (90) | |
SLeX glyco-mimetics | Gal-α-(1 → 1)-β-Man C-fluorinated analogs | 4 | ![]() |
(91) | |
NMSO3 | 5 | ![]() |
Human promyelocytic leukemia | (92) | |
Glyco-peptides | Fluorinated C-manno-peptides | 6 | ![]() |
(93) | |
SLeX-glyco-peptide | 7 | ![]() |
(94) |