Table 1.
Characteristics of FAD gene carriers and age-matched controls. Mean values are given with SDs.
Group | Age (yrs) | Males (%) | Education (yrs) | MMSE (/30) | Anxiety HAD scale (/21) | Depression HAD scale (/21) | NART (/50) | Years to parental age of symptom onset |
---|---|---|---|---|---|---|---|---|
Controls (N = 50) | 36.9 (4.1) | 50% | 15.7 (2.6) | 29.5 (.9) | 6.1(3.8) | 3.1 (2.8) | 31 (9.0) | NA |
Asymptomatic carriers (N = 12) | 37.2 (4.4) | 25% | 13.4 (2.4) | 29.4 (.9) | 5 (4.2) | 1.3 (2.2) | 28.3 (9.3) | 8.5 (3.8) |
p value | .85 | .75 | .01 | .74 | .43 | .02 | .37 | NA |
Group | Age (yrs) | Males (%) | Education (yrs) | MMSE (/30) | Anxiety HAD scale (/21) | Depression HAD scale (/21) | NART (/50) |
---|---|---|---|---|---|---|---|
Controls (N = 28) | 46.8 (6.9) | 46% | 14.3 (2.6) | 29.7 (.5) | 4.9 (3.5) | 2.6 (2.7) | 31.9 (10.3) |
Symptomatic carriers (N = 8) | 47.4 (10.2) | 63% | 13.9 (3.1) | 25.8 (3.4) | 6.3 (4.4) | 2.4 (2.3) | 24.3 (12.6) |
p value | .89 | .69 | .74 | <.001 | .47 | .84 | <.001 |