Table 1.
Reported outcomes in cohorts using PARDS-type inclusion criteria and ≥100 patients.
| Years | Centers | Countries | Cases | Outcomes | Comments | Reference |
|---|---|---|---|---|---|---|
| 1986–1990 | 1 | USA | 100 | Mortality (72%) | PaO2 ≤75 with FiO2 ≥0.5; bilateral infiltrates; 74% immunocompromised | (9) |
| 1990–1991 | 14 | France | 123 | Mortality (60%) | Intubated; FiO2 ≥0.5 on PEEP; bilateral infiltrates | (10) |
| 1993–1995 | 1 | Canada | 131 | Mortality (27%) Ventilator days survivors (8, range 1–27) |
Intubated; PEEP ≥6 and FiO2 ≥0.5 for 12 h | (11) |
| 1997–1998 | 10 | USA, Canada | 232 | Mortality (40%) | Intubated; HFOV | (22) |
| 1996–2000 | 2 | USA | 328 | Mortality (22%) VFD (15 ± 11) |
Non-invasive and intubated; AECC ALI with PF ≤300 | (12) |
| 2004–2005 | 12 | Australia, New Zealand | 117 | Mortality (35%) | Non-invasive and intubated; AECC ALI with PF ≤300 | (13) |
| 2005–2006 | 26 | China | 358 | Mortality (44%) | Any respiratory support; AECC ALI with PF ≤300 | (14) |
| 2000–2007 | 1 | USA | 398 | Mortality (20%) VFD (17, IQR 0–24) |
Intubated; PF ≤300; 192 with bilateral infiltrates | (15) |
| 2007–2010 | 5 | USA | 168 | Mortality (11%) VFD (20, IQR 10–23) |
Intubated; AECC ALI with PF ≤300; excluded SCT | (16) |
| 2009–2010 | 7 | USA, Canada, Belgium, Switzerland, Netherlands | 328 | Mortality (38%) | Intubated; HFOV | (23) |
| 2010–2011 | 21 | Spain | 146 | Mortality (26%) | Intubated; AECC ARDS with PF ≤200 | (17) |
| 2009–2011 | 7 | Italy, Spain, France, Austria, Netherlands | 221 | Mortality (17%) ECMO/death (19%) |
Intubated; Berlin ARDS with PF ≤300; age 1–18 months | (18) |
| 2009–2013 | 1 | USA | 312 | Mortality (22%) | Intubated; Berlin ARDS with SpO2 cutoffs | (19) |
| 2008–2014 | 5 | USA | 299 | Mortality (13%) | Non-invasive and intubated; AECC ARDS with PF ≤200 | (20) |
| 2009–2014 | 12 | USA | 222 | Mortality (60%) Ventilator days survivors (9, IQR 4–16) |
Intubated; SCT | (21) |
| 2011–2014 | 1 | USA | 283 | Mortality (13%) VFD (17, IQR 3–21) Ventilator days survivors (10, IQR 7–17) |
Intubated; AECC ALI and Berlin ARDS with PF ≤300 | (5) |
AECC, American-European Consensus Conference; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; HFOV, high-frequency oscillatory ventilation; PEEP, positive end-expiratory pressure; PF, PaO2/FiO2; SCT, stem cell transplant; VFD, ventilator-free days.