Table 1.
Characteristics of participants with CP
| MRC | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ID | Sex | Age (years) | Rx | MRI | GMFCS | FMSTOTAL | Plantar | Dorsi | mAsh | Penn |
| CP‐1 | F | 19 | PVWMI+ | I | 17 | 5 | 4 | 0 | 1 | |
| CP‐2 | M | 29 | Baclofen, citalopram | PVWMI++/CM | I | 16 | 4 | 4 | 3 | 3 |
| CP‐3 | M | 25 | PVWMI ++ | I | 18 | 5 | 5 | 1+ | 1 | |
| CP‐4 | F | 31 | Venlafaxine | Contraindication | II | 10 | 5 | 4 | 1+ | 2 |
| CP‐5 | F | 34 | PVWMI ++ | IV | 3 | 1 | 2 | 2 | 1 | |
| CP‐6 | M | 48 | Citalopram, tolterodine | PVWMI ++ | III | 3 | 3 | 1 | 3 | 2 |
| CP‐7* | F | 28 | Normal | II | 14 | 5 | 4 | 1 | 1 | |
| CP‐8* | F | 33 | PVWMI ++/DGMI | III | 6 | 4 | 4 | 3 | 2 | |
| CP‐9 | F | 20 | PVWMI ++ | III | 5 | 1 | 0 | 1 | 1 | |
| CP‐10 | M | 26 | PVWMI +/CM | II | 7 | 2 | 1 | 0 | 1 | |
| CP‐11* | F | 19 | Sertraline, clonazepam | PVWMI ++/CM | IV | 3 | 2 | 1 | 1 | 2 |
| CP‐12 | M | 23 | PVWMI + | IV | 3 | 2 | 4 | 1 | 1 | |
| CP‐13 | M | 42 | PVWMI + | III | 4 | 2 | 4 | 1 | 2 | |
| CP‐14 | F | 38 | Normal | III | 9 | 1 | 2 | 1+ | 1 | |
| CP‐15 | F | 51 | Amitriptyline, citalopram, phenytoin, flunarizine | PVWMI +++/CVA | II | 9 | 1 | 3 | 2 | 2 |
| CP‐16 | F | 56 | PVWMI + | I | 17 | 5 | 5 | 0 | 1 | |
| CP‐17 | M | 30 | PVWMI ++ | II | 14 | 4 | 1 | 1 | 1 | |
Columns represent the participant demographics (Sex & Age), daily medications (Rx), the MRI findings, the Gross Motor Functional Classification System (GMFCS) rating, the total Functional Mobility Scale (FMSTOTAL) score with a maximum score of 18, the strength (MRC) of the plantarflexors (Plantar) and dorsiflexors (Dorsi) with a maximum score of 5, the modified Ashworth score (mAsh) for the plantarflexors with a maximum score of 5 and the Penn Spasm Frequency scale (Penn) where 1 = mild spasms induced by stimulation, 2 = infrequent full spasms occurring < 1 h–1, 3 = spasms occurring > 1 h–1).
*The three CP participants from whom motor unit data were not obtained. PVWMI = periventricular white matter injury, CM = cerebral malformations, DGMI = deep grey matter injury, CVA = cerebrovascular accident.