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. 2016 Apr 10;594(10):2629–2645. doi: 10.1113/JP271915

Figure 1. ASIC1a homomers and 1a/2a heteromers have slow desensitization and fast deactivation .

Figure 1

A, example responses from outside‐out patches expressing GluA2 (left), rat ASIC1a (middle) or ASIC1a/2a (right) to a 5 s agonist exposure. B, summary of weighted time constants of desensitization from each construct. C, example responses from GluA2 (left), rat ASIC1a (middle) or ASIC1a/2a (right) to a 1 ms (black traces) or 5 s agonist application (grey traces). Same patches and agonist concentrations as (A). Solution exchange current from each patch for 1 ms (black traces) or 5 s (grey traces) jumps are shown above. D, summary of deactivation time constants for each construct tested.