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. 2016 Apr;28(2):228–234. doi: 10.21147/j.issn.1000-9604.2016.02.12

Table 2.

The RCTs on postoperative therapy for early-stage cervical cancer with high- or intermediate-risk factors for recurrence

Author Year No. of patients Recurrent rate (%) DFS/OS (month)
RCT, randomized controlled trial; CCRT, concurrent chemoradiation therapy; RT, radiation therapy; CT, chemotherapy; OBS, observation; DFS, disease free survival; OS, overall survival; HR, hazard retio; CI, confidence interval. *, P<0.05; **, P<0.01.
Curtin et al. (12) 1996 CT alone: 44; CCRT: 45 20; 22 3-y: 80/85; 3-y: 70/75
Peters et al. (13) 2000 CCRT: 127; RT: 116 Not described 4-y: 80**/81**; 4-y: 63/71
Rotman et al. (14) 2006 RT: 137; OBS: 140 HR, 0.54*; 90% CI, 0.35-0.81 Not described
Sehouli et al. (15) 2012 CT followed by RT: 132; CCRT: 131 Not described 2-y/5-y: 87.2/85.8; 2-y/5-y: 81.8/78.9