Table 5.
The response rate of each regimen for advanced or recurrent cervical cancer
Clinical trial | Regimen | RR (%) | PFS (month) | OS (month) |
GOG; Gynecologic Oncology Group; RR, response rate; PFS, progression free survival; OS, overall survival; PTX, paclitaxel; CDDP, cisplatin; GEM, gemcitabine; *, P<0.05; **, P<0.01. | ||||
GOG169 (33) | PTX + CDDP | 36.0** | 4.8** | 9.7 |
CDDP alone | 19.0 | 2.8 | 8.8 | |
GOG179 (34) | CDDP alone | 13.0 | 2.9 | 6.5 |
topotecan + CDDP | 27.0* | 4.6* | 9.4* | |
GOG204 (35) | GEM + CDDP | 22.3 | – | 10.3 |
topotecan + CDDP | 23.4 | – | 10.3 | |
vinorelbine + CDDP | 25.9 | – | 10.0 | |
PTX + CDDP | 29.1 | – | 12.9 |