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Disruption of MAGL or glutamate reuptake does not enable spread of endocannabinoid signaling from PF–PC synapses to PF–GC synapses. A, The stimulation electrode was placed in molecular layer to activate PFs that innervate PCs and GCs. B, The tetanic stimulation in molecular layer induced PTP of EPSCs in GCs in wild-type control slices, slices treated with JZL184 (0.3 µm) or TBOA (100 µm; n = 8–9; p > 0.05).
