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. 2016 May 13;6:25780. doi: 10.1038/srep25780

Figure 5. mTOR activity was affected by altered Notch1 or Notch intracellular domain (NICD) expression.

Figure 5

(a–c) The pS6, a maker for mTOR signal pathway activation, expression (red) in control, Notch1-conditional knockout (cKO) or NICD-conditional overexpression (cOE) mouse hippocampus respectively. (d–f) The pS6 expression (red) in Cre-GFP infected cells of the olfactory bulb in wild type, Notch1 floxed, or NICD floxed mice respectively. notch1 was knocked out or NICD was overexpressed in the GFP-positive cell of Notch1 floxed or NICD floxed mice respectively.