. Author manuscript; available in PMC: 2016 May 13.

Published in final edited form as: Pharmacogenomics. 2015;16(4):323–332. doi: 10.2217/pgs.14.182

Table 1.

Patients’ characteristics.

		Group N	Group O	p-value
Age at therapy (years)	(Mean, range)	14.0 (5–20)	11.8 (5–22)	0.042^†

Sex	(Male/female)	18/10	20/16	0.481

Diagnosis	Osteosarcoma	17	24	0.182^‡
	Neuroblastoma	1	3
	Brain tumor	4	8
	Germ cell tumor	6	1

Cumulative cisplatin dose (mg/m²)	(Mean, range)	420 (161–560)	412 (120–644)	0.766^†

Infusion rate (mg cisplatin/min)	(Median, 25th– 75th percentile)	0.0278 (0.0278–0.333)	0.0278 (0.0278–0.1940)	0.346^§

Treatment duration (days)^¶	(Median, 25th– 75th percentile)	143 (130–160)	155 (90.5–201)	0.511^§

^†

t-test.

^‡

Fisher’s exact test.

^§

Mann–Whitney U test.

^¶

Time interval between first and last cisplatin administration of therapy.