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. 2016 May 13;6:25901. doi: 10.1038/srep25901

Figure 7. HBx contributes to establish an active cccDNA chromatin state.

Figure 7

The viral HBx protein plays a key role in the establishment of an active cccDNA chromatin state by regulating the recruitment of chromatin modifying enzymes, including LSD1 and Set1A, as demonstrated here.