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. Author manuscript; available in PMC: 2016 May 13.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Apr 2;35(5):1218–1225. doi: 10.1161/ATVBAHA.115.305476

Table 1.

Severity of Necrosis in Mice after Hindlimb Ischemia (HLI)

Genotype n Mice with any
necrosis		 Necrosis Grade
I II III
Il21r (+/+) 9 2/9 (22) 2/9 (22) None None
Il21r (−/−) 12 5/12 (42) 3/12 (25) 1/12 (8.3) 1/12 (8.3)

Necrosis grade is from 0 through 4, as described in Methods. Values are expressed as number of mice affected in each category/total number of mice in the category (%). Distribution is to the right. IL21R knockout mice showed a higher necrosis rate compared to the wide type littermates after HLI though not statistical different.