Table 1.
Genotype | n | Mice with any necrosis |
Necrosis Grade | ||
---|---|---|---|---|---|
I | II | III | |||
Il21r (+/+) | 9 | 2/9 (22) | 2/9 (22) | None | None |
Il21r (−/−) | 12 | 5/12 (42) | 3/12 (25) | 1/12 (8.3) | 1/12 (8.3) |
Necrosis grade is from 0 through 4, as described in Methods. Values are expressed as number of mice affected in each category/total number of mice in the category (%). Distribution is to the right. IL21R knockout mice showed a higher necrosis rate compared to the wide type littermates after HLI though not statistical different.