Table 4. Allelic association analysis of rs153109 in the different subgroups of the GeneID-combined population.
Population | SNP-allele | N | MAF | Phwe | Pobs | Padj | OR (95%CI) | ||
---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | ||||||
CAD-early-onset | rs153109C | 847 | 2707 | 0.400 | 0.379 | 0.072 | 0.116 | 0.389 | 1.06 (0.93–1.22) |
CAD-late-onset | rs153109C | 2157 | 2707 | 0.404 | 0.379 | 0.072 | 0.013 | 0.330 | 1.07 (0.93–1.24) |
CAD-anatomical | rs153109C | 1205 | 2707 | 0.393 | 0.379 | 0.072 | 0.235 | 0.622 | 1.04 (0.90–1.20) |
CAD-clinical | rs153109C | 1799 | 2707 | 0.409 | 0.379 | 0.072 | 0.004 | 0.160 | 1.09 (0.97–1.24) |
CAD, coronary artery disease; MAF, minor allele frequency; Phwe, P value from the Hardy-Weinberg equilibrium tests; Pobs, observed P value; Padj, P value adjusted by the covariates; OR, odds ratio after adjustment.