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. 2016 May 12;6:25782. doi: 10.1038/srep25782

Table 6. Genotypic association analysis of rs153109 and the LN-transformed Gensini scores in 1488 CAD patients.

SNP-allele Quantitative trait association
Case control association
beta SE r2 Pobs Padj RAF (n)
Pobs Padj OR (95%CI)
1st(245) 4th(394)
rs153109C 0.002 0.014 0.008 0.587 0.277 0.391 0.386 0.854 0.646 0.94 (0.74–1.21)

The 1st and 4th quartiles of the LN [Gensini score] distribution were used to perform the case control association analysis. The 1st quartile was defined as the quartile with the lowest Gensini scores, and the 4th quartile was defined as the quartile with the highest Gensini scores. Pobs, observed P value; Padj, P value adjusted by the covariates; OR, odds ratio after adjustment; the Padj values and OR values were obtained using a multivariate logistic regression analysis.