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S1P receptors and their coupled G proteins
| Receptor | Other name1 | Coupled G protein |
|---|---|---|
| S1P1 | EDG1 | Gi/o |
| S1P2 | EDG5 | G12/13, Gi/o, Gs, Gq |
| S1P3 | EDG3 | Gq, Gi/o, G12/13 |
| S1P4 | EDG6 | Gs, Gq, G12/13 |
| S1P5 | EDG8 | Gs, Gq, G12/13 |
: EDG, endothelial differentiation gene
