. 2016 May 12;8:54. doi: 10.1186/s13148-016-0219-0

Table 5.

Significant mediating effects of gene methylation on IL-13 outcome

Gene	CpG site	DNA methylation				IL-13 outcome							Mediation effect
		R ²	Storm32			R ²	DNA methylation			Storm32			Mediation effect
		R ²	Effect (a)	SE	p val.	R ²	Effect (b)	SE	p val.	Effect (c')	SE	p val.	Effect (ab*)	Boot SE	Boot LLCI	Boot ULCI	Standardized Effect
LCK	cg17078393	0.2561	0.0659	0.0202	0.0027	0.1906	0.1831	0.1123	0.1133	0.0144	0.0146	0.3331	0.0121	0.0087	0.0003	0.0348	0.157233
LCK	cg05350315	0.1949	0.0711	0.026	0.0101	0.1727	0.1235	0.0883	0.1721	0.0177	0.0142	0.223	0.0088	0.0068	0.0001	0.028	0.144773

None of the mediation effects survived Bonferroni correction