Fig. 3.

The ketogenic diet reduces expression of immune inhibitory receptors and ligands expressed in glioma tumors. Expression of the immune inhibitory receptors, PD-1 (a) and CTLA-4 (b) on infiltrating CD8 T cells isolated from tumors from mice fed each diet were assessed. Expression of the immune inhibitory ligands, CD86 (c) and PD-L1 (d), on GL261-Luc2 tumor tissue was also assessed. N = 5; student’s two tailed t-test; *p < 0.05; **p < 0.01; ****p < 0.0001