Fig. 5.

Expression profiles of phosphorylated and total Akt and Erk in HL-60 cells treated with ATRA and VD3, each alone or in combination with dasatinib. After treatment with 1 μM ATRA and 100 nM VD3, each alone or in combination with 300 nM dasatinib for 24 h, the alterations of the expression level of phosphorylated and total Akt and Erk proteins were evaluated by western blotting method as described in “Methods” section