Table 3.
Adverse events (All cycles)
| N = 12 | CTC-AE grade (Ver. 4.03) | ||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 3/4 (%) | |
| Leukopenia | 1 | 3 | 3 | 0 | 3 (25 %) |
| Neutropenia | 2 | 3 | 3 | 0 | 3 (25 %) |
| Anemia | 4 | 1 | 1 | 0 | 1 (8 %) |
| Thrombocytopenia | 4 | 0 | 1 | 0 | 1 (8 %) |
| Febrile Neutropenia | 0 | 0 | 1 | 0 | 1 (8 %) |
| Hypoalbuminemia | 7 | 1 | 0 | 0 | 0 (0 %) |
| T-Bil elevation | 1 | 1 | 0 | 0 | 0 (0 %) |
| AST elevation | 6 | 0 | 0 | 0 | 0 (0 %) |
| ALT elevation | 4 | 0 | 0 | 0 | 0 (0 %) |
| ALP elevation | 4 | 0 | 0 | 0 | 0 (0 %) |
| Cre elevation | 3 | 0 | 0 | 0 | 0 (0 %) |
| Hyperkalemia | 2 | 0 | 0 | 0 | 0 (0 %) |
| Hypercalcemia | 2 | 0 | 0 | 0 | 0 (0 %) |
| Hyponatremia | 2 | 0 | 0 | 0 | 0 (0 %) |
| Fatigue | 3 | 1 | 1 | 0 | 1 (8 %) |
| Anorexia | 4 | 3 | 1 | 0 | 1 (8 %) |
| Weight loss | 1 | 1 | 0 | 0 | 0 (0 %) |
| Nausea | 1 | 2 | 1 | 0 | 1 (8 %) |
| Vomiting | 2 | 0 | 0 | 0 | 0 (0 %) |
| Constipation | 2 | 4 | 0 | 0 | 0 (0 %) |
| Perforation (colon) | 0 | 0 | 1 | 0 | 1 (8 %) |
| Hypertension | 1 | 2 | 0 | 0 | 0 (0 %) |
| Epistaxis | 3 | 0 | 0 | 0 | 0 (0 %) |
| Stroke | 0 | 1 | 0 | 0 | 0 (0 %) |
| Urticaria | 1 | 1 | 0 | 0 | 0 (0 %) |
| Pruritus | 2 | 0 | 0 | 0 | 0 (0 %) |
| Pneumonitis | 2 | 0 | 0 | 0 | 0 (0 %) |
CTC-AE common terminology criteria for adverse events