Figure 9.

Qualitative Microglial Morphology. Zoomed in images of cells from Figure 8. a) An example of ramified microglia showing thin radially expanded morphology. b) Activated microglia around aCSF perfused microdialysis probes showing reduced number of basal and apical processes and a few elongated processes towards the implant. c) Typical microglia around Dex perfused microdialysis probes show radially projected processes similar to ramified microglia, however, the processes appear thicker with increased short apical processes giving it a “bushier” morphology. d) In one instance around a Dex perfused microdialysis probe, microglia show substantially reduced number of processes and greater encapsulation of blood vessels. Note: d is the same animal, Dex concentration, and probe as (c) (other side of the probe). Scale = 100 μm.