Table 1.
Baseline Characteristics of 33 HIV-Infected Men With Recent and Chronic HCV Infection
| Characteristic | Recent HCV n = 21 | Chronic HCV n = 12 | P Value |
|---|---|---|---|
| Median age (IQR), years | 36 (31–46) | 52 (38–55) | .007 |
| Race | |||
| White (%) | 12 (57) | 7 (58) | .6 |
| Black (%) | 4 (19) | 2 (17) | |
| Hispanic (%) | 5 (24) | 3 (25) | |
| HIV parameters | |||
| Median duration of HIV infection (IQR), years | 7 (4–12) | 10 (4–30) | .1 |
| Median CD4 count (IQR), cells/µL | 691 (537–808) | 710 (272–847) | .6 |
| Receiving cART (%) | 20 (95) | 12 (100) | .4 |
| Detectable HIV viremia (%) | 7 (33) | 8 (67) | .06 |
| STI | |||
| Reactive RPR (%) | 13 (62) | 2 (17) | .1 |
| Urethral STI test performed (%)a | 0/14 | 0/4 | – |
| HCV status | |||
| Primary infection (%) | 17 (81) | 12 (100) | .3 |
| Reinfection (%) | 4 (19) | 0 | |
| HCV genotype | |||
| 1a (%) | 20 (95) | 9 (75) | .3 |
| 1b (%) | 1 (5) | 1 (8) | |
| 2b (%) | 0 | 1 (8) | |
| 3a (%) | 0 | 1 (8) | |
| Route of HCV acquisition | |||
| Sex only (%) | 13 (62) | 6 (50) | .5 |
| Sex + IDU (%) | 8 (38) | 6 (50) | |
| Median ALT (IQR), U/L | 231 (87–492) | 62 (46–105) | .002 |
| Median blood HCV VL (IQR), log10 IU/mL | 5.52 (4.13–6.24) | 6.62 (6.21–6.93) | .006 |
Abbreviations: ALT, alanine aminotransferase; cART, combination antiretroviral therapy; HCV, hepatitis C virus; HIV, human immunodeficiency virus; IDU, injection drug use; IQR, interquartile range; IU, international units; n, number; RPR, rapid plasma regain; STI, sexually transmitted infection; VL, viral load.
a Nucleic acid amplification testing for Chlamydia and Neisseria gonorrhea was performed in 14 (67%) patients with recent HCV and 4 (33%) patients with chronic HCV.