. 2016 Mar 11;3(2):ofw057. doi: 10.1093/ofid/ofw057

Table 3.

Factors Associated With Detection of HCV in 59 Semen Samples From HIV-Infected Men With Recent and Chronic HCV Infection

Characteristic	HCV Detected n = 16	HCV not Detected n = 43	P Value
HCV status
Recent (%)	8 (21)	30 (79)	.2
Chronic (%)	8 (38)	13 (62)
Primary infection (%)	14 (26)	40 (74)	.6
Reinfection (%)	2 (40)	3 (60)
Time from HCV onset to semen donation (IQR), median weeks^a	8 (5–11)	9 (6–17)	.4
Median ALT (IQR), U/L^b	107 (66–507)	99 (60–222)	.3
Volume of semen (IQR), mL	1.5 (0.9–3.6)	2.1 (1.2–2.8)	.8
Semen HCV VL (IQR), log₁₀ IU/mL	1.49 (1.20–2.05)	–	–
Median blood HCV VL (IQR), log₁₀ IU/mL^b	6.36 (6.18–6.93)	5.47 (4.26–6.38)	.002
Median paired blood and semen Δ HCV VL (IQR), log₁₀ IU/mL	5.08 (4.34–5.65)	–	–

Abbreviations: ALT, alanine aminotransferase; Δ, difference; HCV, hepatitis C virus; n, number; IQR, interquartile range; IU, international units; VL, viral load.

^a In men with recent HCV only.

^b Levels at the time of semen donation.