Fig 5. Mycoplasma-specific serum antibody responses were higher in infected CD25⁺ cell-depleted mice as compared to infected control mice.

Mice were given anti-CD25 depleting antibody (CD25⁺ Cell Depleted) or PBS (Control) one day prior to infection with M. pulmonis, followed by antibody or PBS at day 6 post-infection. Uninfected mice were included for comparison. At 14 days post-infection, M. pulmonis specific titers for IgM, IgG and IgA were determined. Data were analyzed after log transformation. An asterisk (*) represents a significant (P ≤ 0.05) difference antibody levels in CD25⁺ cell-depleted mice versus the other groups. Vertical bars and error bars represent means +/- SE (n = 16).