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. 2016 May 13;11(5):e0155438. doi: 10.1371/journal.pone.0155438

Fig 5. HEXIM is a regulator of Ci.

Fig 5

(A) Wing phenotype in WT, rn-Gal4>RNAi Ci and rn-Gal4>RNAi Ci; RNAi Hexim flies. Red arrows refer to vein or intervein defects. For single or double mutants, 100% of flies displayed the phenotype (over > 200 mutants flies scored). Immuno-localization of Ci155 and Ptc in the wing disc of WT (B), rn-Gal4>RNAi Hexim (C) and rn-Gal4>RNAi Ci (D) flies. The reduced levels of Ci155 in the A-P stripe (white arrow) causes aberrations at the intervein 3 and 4. Immuno-localization of Ci155, Ptc and HEXIM in WT (E) and in rn-Gal4>RNAi Hexim; RNAi Ci double mutant (F) wing discs. (G) Immuno-localization of Ci155 and Dpp in WT and in rn-Gal4>RNAi Hexim; RNAi Ci double knockdown. (H) X-Gal staining of dpp-lacZ reporter in WT and in rn-Gal4>RNAi Hexim; RNAi Ci mutant.