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. 2016 May 13;12(5):e1006032. doi: 10.1371/journal.pgen.1006032

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© 2016 Chambonnier et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Current model for the regulatory elements influencing the expression of two sRNAs, RsmY and RsmZ. See text for details. (B) The multicomponent signal transduction system made of the LadS hybrid HK and the GacS/GacA TCS. In the presented model sustained by results obtained in the present study, this multicomponent signal transduction system made of the LadS hybrid HK and the GacS/GacA TCS forms a multiple-input system probably reflecting the variability of environmental conditions P. aeruginosa is faced with and may result in a range of gradations of chronic infection. IM (Inner Membrane), P (Periplasm), C (Cytoplasm).