Table 1. Patient characteristics by treatment group.
RT*: Patients in the adjuvant therapy group had either traditional fractioned radiotherapy (XRT, n: 175) or stereotactic radiosurgery (SRS, n: 88).
| Patient Characteristics | Predictors of | |||||
| Total | RT* | No RT | p-value | RT* over no RT | ||
| Variable | (n=1964) | (n=263) | (n=1701) | Odds Ratio (95%CI) | ||
| Age, n (%) | 0.0300 | |||||
| 66-74 | 1058 (53.87) | 158 (60.08) | 900 (52.91) | Reference | ||
| 75+ | 906 (46.13) | 105 (39.92) | 801 (47.09) | 0.730 (0.548-0.973) | ||
| Gender, n (%) | 0.0006 | |||||
| Male | 633 (32.23) | 109 (41.44) | 524 (30.81) | Reference | ||
| Female | 1331 (67.77) | 154 (58.56) | 1177 (69.19) | 0.731 (0.547-0.978) | ||
| Race, n (%) | 0.7113 | |||||
| White | 1615 (82.23) | 214 (81.37) | 1401 (82.36) | Reference | ||
| Black | 166 (8.45) | 21 (7.98) | 145 (8.52) | 0.865 (0.515-1.453) | ||
| Other | 183 (9.32) | 28 (10.65) | 155 (9.11) | 1.006 (0.636-1.589) | ||
| Marital status, n (%) | 0.0013 | |||||
| Married | 1044 (53.16) | 164 (62.36) | 880 (51.73) | Reference | ||
| Unmarried/unknown | 920 (46.84) | 99 (37.64) | 821 (48.27) | 0.692 (0.515-0.929) | ||
| Laterality, n (%) | 0.4254 | |||||
| Right | 764 (38.90) | 96 (36.50) | 668 (39.27) | Reference | ||
| Left | 773 (39.36) | 102 (38.78) | 671 (39.45) | 1.073 (0.786-1.465) | ||
| Other/Unknown | 427 (21.74) | 65 (24.71) | 362 (21.28) | 0.846 (0.573-1.248) | ||
| Grade | <.0001 | |||||
| Grade I | 136 (6.92) | 11 (4.18) | 125 (7.35) | Reference | ||
| Grade II/III | 46 (2.34) | 18 (6.84) | 28 (1.65) | 5.586 (2.135-13.589) | ||
| Unknown | 1782 (90.73) | 234 (88.97) | 1548 (91.01) | 1.836 (0.944-3.589) | ||
| Surgery extent, n (%) | <.0001 | |||||
| Local excision | 524 (26.68) | 59 (22.43) | 465 (27.34) | Reference | ||
| Partial excision | 352 (17.92) | 92 (34.98) | 260 (15.29) | 1.312 (0.912-1.889) | ||
| Gross total excision | 1088(55.40) | 112 (42.59) | 976 (57.38) | 3.230 (2.327-4.484) | ||
| Diagnosis year | <.0001 | |||||
| 2000-2003 | 57 (2.90) | 28 (10.65) | 29 (1.70) | Reference | ||
| 2004 | 279 (14.21) | 33 (12.55) | 246 (14.46) | 0.131 (0.064-0.268) | ||
| 2005 | 326 (16.60) | 52 (19.77) | 274 (16.11) | 0.214 (0.108-0.424) | ||
| 2006 | 328 (16.70) | 38 (14.45) | 290 (17.05) | 0.154 (0.076-0.312) | ||
| 2007 | 327 (16.65) | 38 (15.45) | 289 (16.99) | 0.139 (0.069-0.282) | ||
| 2008 | 316 (16.09) | 43 (16.35) | 273 (16.05) | 0.172 (0.085-0.346) | ||
| 2009 | 331 (16.85) | 31 (11.79) | 300 (17.64) | 0.102 (0.049-0.211) | ||
| Tumor size, n (%) | <.0001 | |||||
| 0-49 cm | 928 (47.25) | 93 (35.36) | 835 (49.09) | Reference | ||
| 50+ cm | 520 (26.48) | 96 (36.50) | 424 (24.93) | 1.850 (1.332-2.567) | ||
| unknown | 516 (26.27) | 74 (28.14) | 442 (25.98) | 1.316 (0.931-1.860) | ||
| Gagne comorbidity score | ||||||
| Mean (SD) | 0.56 (1.23) | 0.62 (1.41) | 0.55 (1.20) | One unit increase | ||
| Median (Q1-Q3) | 0.31 (-0.20, 1.00) | 0.33 (-0.20, 1.16) | 0.30 (-0.20, 1.00) | 0.5080 | 1.005 (0.902-1.120) | |