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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: J Neurovirol. 2015 Nov 13;22(3):358–365. doi: 10.1007/s13365-015-0403-6

Figure 2.

Figure 2

Saturation analysis for system XAG and xc- glutamate uptake in glial and neuronal preparations from striatum of gp120 and wild-type (WT) mice. These glial (i.e., glial plasmalemmal vesicles; GPV) and neuronal (i.e., synaptosomes; SYN) preparations are enriched in small vesicles pinched off from glial membranes and nerve endings, respectively. Analysis revealed a significant (p<0.05) reduction in the Vmax of systems XAG and xc- in both (A) GPV and (B) SYN fractions from gp120 mice compared to WT. There were no significant group differences in the Km (affinity) for XAG or xc- glutamate uptake in GPV and SYN. Data are expressed as mean ± SEM (n=4/preparation/group).