Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 27;37(6):1587–1593. doi: 10.3892/ijmm.2016.2580

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Gu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Effect of miR-130b on the proliferation of U251 cells in vitro. (A) U251 cell proliferation was significantly induced by transfection with miR-130b mimic (mimic) and inhibited by transfection with miR-130b inhibitor (inhibitor) at 48 and 72 h. (B and C) Upregulation of miR-130b markedly increased the number of surviving colonies and downregulation of miR-130b reduced the number of surviving colonies of U251 cells compared with the negative control (NC) groups. (D) The results of the cell cycle assay revealed that the upregulation of miR-130b decreased the percentage of cells in the G0–G1 phase and downregulation of miR-130b increased the percentage of cells in the G0–G1 phase. Data are means + SD of 3 independent experiments. *P<0.05 vs. NC group; #P<0.05 vs. NC group.