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Effect of estrogen on the proliferation of periodontal ligament stem cells (PDLSCs) isolated from rats in the ovariectomized (OVX) group over a period of 8 days (n=12 wells/plate, means ± SD). At the same time-point, *P<0.05, OVX vs. sham or OVX + E2; †P<0.05, OVX + E2 vs. sham; ‡P<0.05, OVX + E2 vs. OVX. Sham, sham-operated group.
