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. Author manuscript; available in PMC: 2016 Jun 6.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2006 Jan;141(1):67–70. doi: 10.1002/ajmg.b.30229

Fig. 2.

Fig. 2

Conservation, genotyping and frequencies of the two PCDH11Y haplotypes in control and affected populations. a: Protein structure and sequence alignment of protocadherins from different species. PCDH9 is the closest homologue of PCDH11 in the protocadherin phylogeny. SPV, signal peptide variations; Tm, transmemebrane domain; CD, cadherin domain; CyDV, cytoplasmic domain variations. b: Genotyping of the two PCDH11Y haplotypes FK and VN by restriction analysis using the enzyme Tsp509 I. c: Frequencies of the PCDH11Y haplotypes FK and VN in the French and Swedish male samples. The French sample sizes are the following: autism spectrum disorder (AU, n =72), obsessive-compulsive disorder (OCD, n = 51), bipolar disorder (BP, n = 61), schizophrenia (SCZ, n = 61) and controls (C, n = 86). The Swedish sample sizes are 61, 38 and 47 for ADHD, autism spectrum disorder (AU) and controls (C), respectively.