Table 2.

Multivariable analysis of hyperglycemic clamp outcomes by metabolic syndrome components as continuous variables.

	Insulin Sensitivity Index		AUCΔInsulin0-10		Disposition Index
	β (95% CI)	P	β (95% CI)	P	β (95% CI)	P
Age (years)	−0.17 (−0.32,−0.01)	0.033	−1.7 (−7.1, 3.7)	0.54	−31.4 (−66.6, 3.9)	0.08
Sex*	3.1 (−6.5, 0.4)	0.079	−97.5 (−220.0, 25.2)	0.12	−746.5 (−1546.0, 530)	0.067
Race†	−0.22 (−3.8, 3.3)	0.90	275.6 (150.4, 400.8)	<10−4	1443.2 (589.2, 2297.3)	0.001
Glucose (mmol/L)	−0.57 (−2.6, 1.5)	0.58	−177.8 (−250.3, −105.3)	<10−5	−910.8 (−1402.3, −419.3)	<0.001
Waist circumference (cm)	−0.28 (−0.40, −0.16)	<0.001	−1.3 (−6.0, 3.4)	0.58	−42.8 (−71.3, −14.3)	0.004
HDL Cholesterol (mmol/L)	6.2 (0.9, 11.4)	0.022	20.9 (−168.6, 210.4)	0.83	1187.4 (−65.0, 2439.9)	0.063
SBP (mmHg)	0.02 (−0.07, 0.11)	0.66	−3.0 (−6.3, 0.3)	0.07	−15.1 (−38.3, 8.1)	0.20
Triglycerides (mmol/L)	−0.69 (−2.3, 0.93)	0.40	16.5 (−40.3, 73.3)	0.57	106.4 (−271.3, 483.9)	0.58
ISI (mg/kg/min per μU/mL•100)	NA		−13.9 (−21.0, −6.9)	<0.001	NA

β-coefficient represents change in outcome per unit change in variable.

^*Female referent

^†Caucasian referent