Table 5. Adjusted Means of Anthropometric Measurements for the Genotype and Allele Combinations of ADRA2A rs553668 and ACEI/D SNPsa,b.
Variables | Number | WHR | BMI, kg/m2 | TBF, % |
---|---|---|---|---|
Genotype combinations | ||||
AA/DD | 8 | 0.86 ± 0.02 | 26.98 ± 1.65 | 32.10 ± 3.60 |
AA/II | 11 | 0.85 ± 0.02 | 22.71 ± 1.42 | 21.88 ± 3.11 |
GG/DD | 16 | 0.85 ± 0.01 | 22.87 ± 1.19 | 22.79 ± 2.60 |
GG/II | 12 | 0.79 ± 0.02 | 21.66 ± 1.37 | 19.67 ± 3.00 |
P value | 0.01c | 0.19 | 0.36 | |
Allele combinations | ||||
A/D | 105 | 0.84 ± 0.01 | 24.66 ± 0.50 | 26.12 ± 1.08 |
A/I | 89 | 0.86 ± 0.01 | 24.30 ± 0.54 | 24.71 ± 1.17 |
G/D | 83 | 0.84 ± 0.01 | 23.09 ± 0.56 | 23.00 ± 1.22 |
G/I | 151 | 0.84 ± 0.01 | 23.73 ± 0.42 | 24.15 ± 0.90 |
P value | 0.105 | 0.26 | 0.51 |
Abbreviations: BMI, body mass index; TBF, total body fat; WHR, waist-to-hip ratio.
aBMI and TBF were log-transformed before analysis using univariate analysis of variance (general linear model), adjusted for co-variates: age, gender, and ethnicity.
bValues are presented as adjusted mean ± SEM (estimated marginal means ± standard error of the mean).
cP value significant at < 0.05.