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. 2016 Jan 14;150(2):418–428. doi: 10.1093/toxsci/kfw005

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Published by Oxford University Press on behalf of the Society of Toxicology 2016. This work is written by US Government employees and is in the public domain in the US.

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FIG. 6. — Alteration in gene expression in SAEC due to CoO and La₂O₃ nanoparticles. cDNA generated from RNA was isolated from SAEC treated with 0.0, 5.0, 25.0, and 50.0 µg/ml administered dose for 6 h with CoO and La₂O₃ nanoparticles. cDNA was then assayed with TaqMan qRTPCR for the following genes: (A) NOS2, (B) MT3, (C) PTGS2(COX2), and (D) SOD3. Samples were normalized to internal control 18 s. The values represent a fold induction compared to 0.0 µg/ml control (1.0). n = 3, * indicates P < .05 compared to La₂O₃ nanoparticles at the same administered dose.