Figure 22.
Intracellular recordings with SiNW FETs. (a) Schematics of cellular recording from a cardiomyocyte monolayer on PDMS support (left) and extracellular (middle) and intracellular (right) NW/cell interfaces. Inset is an SEM image of the kinked nanowire device. Purple lines denote the cell membrane and NW lipid coating. (b) Plots corresponding to (i) extracellular, (ii) extracellular to intracellular transition, and (iii) steady-state intracellular recording. Reprinted with permission from Ref. 54. Copyright 2010 American Association for the Advancement of Science. (c) A branched SiO2 nanotube integrated on top of a SiNW transistor. Reprinted with permission from Ref. 556. Copyright 2012 Nature Publishing Group. (d) Optical image of a kinked NW probe (left) and patch-clamp pipette (right) recording from the same cell. Reprinted with permission from Ref. 558. Copyright 2014 Nature Publishing Group.