Fig. 3.

Ketamine treatment induces an altered voiding pattern. Overall, the ketamine-treated group (combined week 2–12 data) had significantly more PVS numbers per filter paper than the control group (A) but had significant smaller sizes of PVSs than the control group (B). Along the weekly time course, the ketamine-treated group consistently yielded a higher PVS number but lacked statistical significance, as shown in C. Ketamine induced a significantly smaller PVS size, even at week 2, as shown in D. The number of filter papers for A and B was 110 papers; the filter paper number for C and D was 10 papers/wk except for weeks 13 and 16, for which the number was 5 papers/wk. Error bars are SDs. *P < 0.05.