Fig. 1.

Characteristics of male control and diabetic Zucker diabetic fatty (ZDF) rats. A: body weight of control and diabetic rats at 16 and 27 wk of age. Body weights of diabetic rats were significantly increased at both ages. Body weights are means ± SE of 40 animals at 16 wk of age and 28 animals at 27 wk of age. B: body weights of control and diabetic animals measured from 12 wk until 27 wk of age. C: blood glucose levels of control and diabetic rats at 16 and 27 wk of age. Blood glucose levels were significantly increased in diabetic rats at both ages. Glucose levels are means ± SE of 14 animals at 16 wk of age and 11 animals at 27 wk of age. D: blood glucose levels of control and diabetic rats measured from 12 wk through 27 wk of age. E: bladder wet weights of control and diabetic rats at 16 and 27 wk of age. Bladder weights were significantly increased in diabetic rats at both ages. Bladder weights are means ± SE of 10 animals at 16 wk of age and 17 animals at 27 wk of age. Statistical comparisons were made between control and diabetic rats using Student's t-test. *P < 0.05 compared with control rats at same age.